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Osteoblastic bone formation in Y2−/− Y4−/− double knockout micea
| Mice | Mineralizing surface (%, BS) | Mineral apposition rate (μm/day) | Bone, formation rate (μm2/μm/day) |
|---|---|---|---|
| Control | 38.4 ± 12.7 | 1.1 ± 0.2 | 0.41 ± 0.1 |
| Y2−/− Y4−/− | 39.6 ± 7.2 | 1.4 ± 0.2* | 0.58 ± 0.2* |
Data are means ± standard deviations for 9 to 14 mice per group. *, P < 0.05 versus control. BS, bone surface.
