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. 2000 Jun 6;97(13):7482–7487. doi: 10.1073/pnas.120474397

Figure 2.

Figure 2

Transgene expression [β-galactosidase (β-gal)] and inflammatory responses (CD8, MHC I, ED1) in the brain, 60 days after intradermal injection of adenovirus. Rows a–d show brains from animals injected intrastriatally with 1.3 × 107 i.u. of RAd35 (rows a and b) or AdGS46 (rows c and d) at day 0, and intradermally with 5 × 108 i.u. of RAdHPRT (rows a and c), or the equivalent number of particles of psoralen-inactivated RAdHPRT (ps-RAdHPRT, rows b and d) at day 60 (i.e., day 120 postbrain injection). Scale bars and anatomical and immunohistochemical markers shown as for Fig. 1.