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. 2000 Jun 6;97(13):7515–7520. doi: 10.1073/pnas.120177997

Table 1.

α-gal A enzyme activities in transduced murine BM-derived cells

Murine phenotype Treatment α-gal A activity, nmol/h per mg protein
BM cells (24 hr) Progenitor colony cells (14 d) Adherent LTBMCs (15 wk)
Fabry None (mock) 7  ± 0 6  ± 0 19  ± 0
Fabry pG1T/α-gal A 1,630  ± 30* 42  ± 2* 290  ± 7*
Fabry pUMFG/α-gal A/FLAG 2,310  ± 70* 720  ± 16* 790  ± 18*
Wild type None (mock) 2,170  ± 50 3,600  ± 140 NE

Activities were measured 24 hr, 14 days, or 15 weeks after the last transduction, as shown. NE, not examined. *, P < 0.0001 vs. Fabry (mock) group; †, P < 0.0001 vs. pG1T/α-gal A group.