Table 1.
Data regarding the parental strains used for constructing isogenic mutants
| Strain | Country | Disease | cagPAI | vacA | iceA | babA2 |
|---|---|---|---|---|---|---|
| 26695 | U.K. | Gastritis | + | s1b-m1 | 1 | −∗ |
| SS1 | Australia | Gastritis | + | s2-m2 | 2 | − |
| JK43, JK44, JK46, JK51 | Japan | Gastritis | + | s1c-m1 | 1 | + |
| JK23, JK91 | Japan | DU | + | s1c-m1 | 1 | + |
| JK25 | Japan | DU | + | s1c-m1 | 2 | − |
| JK35 | Japan | DU | + | s1c-m1 | 2 | + |
| GI2060, GI2777 | U.S. | Gastritis | + | s1b-m1 | 2 | + |
| GI2895 | U.S. | Gastritis | + | s1a-m1 | 1 | + |
| GI2975 | U.S. | Gastritis | + | s1b-m1 | 1 | + |
| GI2450 | U.S. | DU | + | s1b-m2 | 2 | + |
| GI2826 | U.S. | DU | + | s1a-m2 | 2 | + |
| JK2-41 | Japan | Gastritis | − | s1c-m1 | 2 | + |
| GI2853 | U.S. | Gastritis | − | s2-m2 | 2 | + |
| GI2924 | U.S. | Gastritis | − | s2-m2 | 2 | − |
| GI3009 | U.S. | Gastritis | − | s2-m2 | 1 | − |
| GI2490, GI2685 | U.S. | DU | − | s2-m2 | 2 | − |
*
H. pylori 26695 had reported as babA1 genotype because this has no ability to bind to Lewis b Ag. However, 26695 was classified as babA2 by our PCR techniques because sequence analysis of this strain showed that there was a 10-bp repeat motif in babA gene (HP1243).