Table 1. Biological activities of lobophorolide (1).

Assay organism	IC50, μg/ml
D. salina	0.034
L. thalassiae	0.135
S. aggregatum	Not active*
P. bacteriolytica	Not active*
C. albicans	1.3
C. albicans (amphotericin-resistant strain)	0.5
Human colon tumor cell line HCT-116	0.03

^*Tested up to 0.2 μg/ml.