Table 3. The top 25 residues on the diagonal in Fig. 2 listed by residue number, corresponding epitope, diversity of codons, and diversity of amino acids.
| Residue | Epitope | D(codons) | D(acids) |
|---|---|---|---|
| 135 | A | 0.713 | 0.711 |
| 226 | D | 0.713 | 0.705 |
| 124 | A | 0.699 | 0.685 |
| 262 | E | 0.672 | 0.669 |
| 133 | A | 0.640 | 0.639 |
| 121 | D | 0.634 | 0.630 |
| 276 | C | 0.616 | 0.615 |
| 172 | D | 0.552 | 0.551 |
| 156 | B | 0.544 | 0.536 |
| 278 | C | 0.537 | 0.528 |
| 145 | A | 0.529 | 0.524 |
| 197 | B | 0.514 | 0.505 |
| 189 | B | 0.467 | 0.466 |
| 190 | B | 0.459 | 0.449 |
| 157 | B | 0.453 | 0.451 |
| 196 | B | 0.418 | 0.345 |
| 193 | B | 0.384 | 0.375 |
| 158 | B | 0.365 | 0.359 |
| 144 | A | 0.343 | 0.343 |
| 62 | E | 0.373 | 0.308 |
| 142 | A | 0.341 | 0.332 |
| 131 | A | 0.307 | 0.294 |
| 275 | C | 0.291 | 0.284 |
| 83 | E | 0.288 | 0.276 |
| 299 | C | 0.278 | 0.275 |
We consider a residue to be on the diagonal of Fig. 2 if the difference between its codon and amino acid diversity is <10% of their sum. In total, there are 78 diagonal residues in Fig. 2. Residues in the table are sorted by the sum of their codon and amino acid diversities. Fourteen of these 25 sites were previously identified as being under positive selection (15)