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. 2003 May 19;100(12):7253–7258. doi: 10.1073/pnas.1136854100

Fig. 5.

Fig. 5.

FH-B-TPN cells can replace beta-cell function in NOD-scid STZ-induced diabetic mice. (a) Fed blood glucose levels. Filled circles, transplanted mice (n = 3); open circles, untransplanted mice (n = 4). Values are mean ± SEM. The differences between the two groups were significant on days 25–70 after transplantation (P < 0.0001). (b) Glucose tolerance test performed on the mice in a 70 days after transplantation. Circles, transplanted diabetic mice; triangles, nondiabetic NOD-scid mice. Values are mean ± SEM. The differences between transplanted and nondiabetic mice were not significant at the 30- to 120-min time points (P > 0.2). Untransplanted diabetic mice were hyperglycemic (>350 mg/dl) at all time points (data not shown).