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SB203580 treatment inhibits the growth of SUDHL-4 cells by apoptosis in vivo. (a) There is a significant difference in the growth of tumors in the treated versus the untreated animals. (b) In situ TUNEL assay shows only rare apoptotic (red-brown) signals in SUDHL-4 xenografts of untreated animals. (c) In situ TUNEL assay shows a significant number of apoptotic signals in comparison to untreated animals.
