Effects of probucol on survival. (A) dKO mice (red line, n = 13, chow diet, ref. 1), dKO-P mice (blue line, n = 10, 0.5% probucol diet from conception), and dKO-Pww mice (black line, n = 9, probucol diet from conception until weaning). (B) dKO-P<5 mice (probucol diet administered only after weaning but before 5 weeks of age, green line; n = 9) and dKO-P>5 (probucol diet administered immediately after 5 weeks of age, purple line; n = 7).