Table 1. Mutations present in the RdRp region of the ribavirin-resistant clone.
Nucleotide* | Change | Amino acid change |
---|---|---|
6176 | G → A | G64S |
6652 | G → A | None |
6736 | G → A | None |
6879 | A → G | None |
7132 | G → A | None |
7216 | T → C | None |
Nucleotides 5595-7305 of the resistant virus were subcloned and sequenced.
Nucleotide numbers are from the Mahoney stain of poliovirus type 1