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Effect of lesion and mitogen treatment on proliferative indices in the forebrain. Western blot analysis (Upper) indicates that expression of the proliferation-associated antigen Ki67 is reduced in the olfactory bulb of 192IgG-lesioned animals, and that mitogen injections expand the distribution of BrdUrd-uptaking cells in the SVZ in lesioned animals (A, control, saporin-injected; B, lesioned, 192IgG-injected + EGF).
