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. 2003 Jul 15;31(14):4051–4058. doi: 10.1093/nar/gkg444

Table 1. Comparison of PPAR sequences.

Position in human hPPARγ PPARα     PPARγ   PPARδ  
 
Human
fr074373
fr087148
Human
fr054267
Human
fr07671
Helix3-289 Ser Ser Ser Ser Ser Thr Thr
Helix5-323 Tyr Tyr Tyr His Ile His His
Helix10-449 His His His His His His Asn
HelixAF2-473 Tyr Tyr Tyr Tyr Met Tyr Tyr

Italics specify amino acids that differ from the consensus. Bold specifies amino acids predicted to prevent fatty acid ligand binding.