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. 2003 Aug;71(8):4795–4803. doi: 10.1128/IAI.71.8.4795-4803.2003

FIG. 1.

FIG. 1.

Kinetics of fluid accumulation and CXC chemokine expression in bovine and murine ligated ileal loops. (A and B) Fluid accumulation elicited in bovine (A) and murine ligated (B) ileal loops is shown. Each data point represents the average (±standard deviations) from three independent experiments. Asterisks indicate that the amount of fluid elicited by serotype Typhimurium wild type (IR715; hatched bars) was significantly higher (P < 0.05) than that elicited by the sipA sopABDE2 mutant (ZA21; open bars) and sterile LB broth (solid bars). (C to F) The change in induction (n-fold) of CXC chemokine gene expression in bovine (C and E) or murine (D and F) ileal Peyer's patches infected with wild-type (hatched bars) or sipA sopABDE2 mutant (open bars) strains compared to expression in Peyer's patches inoculated with LB broth at 1 h (C and D) or 8 h (E and F) after inoculation is shown below. Asterisks indicate a significant increase in chemokine mRNA level in loops infected with the wild type (IR715) compared to those inoculated with the sipA sopABDE2 mutant (ZA21).