TABLE 3.
Tissue | C.I. geometric mean
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
wt/wt Kan
|
ΔyopB/wt Kan
|
ΔyopH/wt Kan
|
ΔyopE/wt Kan
|
ΔyopO/wt Kan
|
ΔyopHEMOJ/wt Kan day 5 | ||||||
Day 2 | Day 5 | Day 2 | Day 5 | Day 2 | Day 5 | Day 2 | Day 5 | Day 2 | Day 5 | ||
Ileum | 0.7 | 0.021 | 0.047 | 0.024 | 0.094 | 0.015 | |||||
Cecum | 0.85 | 0.63 | 0.008 | 0.009 | 0.19 | 0.026 | 0.26 | 0.078 | 0.58 | 0.2 | 0.006 |
Colon | 0.45 | 0.01 | 0.014 | 0.073 | 0.24 | 0.005 | |||||
PP | 0.70 | 1.12 | 0.006 | 0.022 | 0.15 | 0.02 | 0.16 | 0.04 | 0.65 | 0.03 | 0.012 |
CL | 0.89 | 0.013 | 0.017 | 0.085 | 0.11 | 0.005 | |||||
MLN | 0.81 | 0.54 | 0.051 | 0.032 | 0.07 | 0.02 | 0.19 | 0.2 | 0.82 | 0.097 | 0.012 |
Geometric mean of the C.I. from six to eight mice pooled from three to four experiments. C.I. for mutant/wild type that were statistically significant from the C.I. for wild type/wild type are indicated as follows: boldface, P < 0.01; underlined characters, P value is between 0.01 and 0.1. wt, wild type.