Table 5.
Ciclosporin* | Age (years)** | Charlson comorbidity index*** | |||||||
Tacrolimus and prednisolon | Ciclosporin and prednisolon | p | ≤58.88 | >58.88 | p | ≤2 | >2 | p | |
N | 9 | 39 | 27 | 26 | 30 | 23 | |||
ESRD-SCL | |||||||||
Limited physical capacity | 0.62 ± 0.18 | 0.82 ± 0.09 | 0.33 | 0.73 ± 0.11 | 0.81 ± 0.11 | 0.62 | 0.63 ± 0.10 | 0.91 ± 0.11 | 0.06 |
Limited cognitive capacity | 0.45 ± 0.15 | 0.59 ± 0.08 | 0.43 | 0.57 ± 0.10 | 0.58 ± 0.10 | 0.93 | 0.46 ± 0.09 | 0.69 ± 0.10 | 0.10 |
Cardiac and renal dysfunction | 0.72 ± 0.19 | 0.82 ± 0.08 | 0.21 | 0.73 ± 0.11 | 0.79 ± 0.11 | 0.71 | 0.62 ± 0.10 | 0.91 ± 0.12 | 0.07 |
Side effects of corticosteroids | 0.67 ± 0.18 | 0.68 ± 0.09 | 0.20 | 0.71 ± 0.11 | 0.58 ± 0.11 | 0.16 | 0.53 ± 0.10 | 0.76 ± 0.12 | 0.16 |
Increased growth of gum and hair | 0.19 ± 0.27 | 0.92 ± 0.09 | 0.02 | 0.74 ± 0.16 | 0.73 ± 0.16 | 0.98 | 0.61 ± 0.15 | 0.87 ± 0.17 | 0.26 |
Transplantation-associated psychological distress | 0.67 ± 0.16 | 0.58 ± 0.08 | 0.60 | 0.66 ± 0.09 | 0.54 ± 0.09 | 0.38 | 0.56 ± 0.09 | 0.64 ± 0.10 | 0.56 |
Total | 0.57 ± 0.14 | 0.73 ± 0.07 | 0.32 | 0.69 ± 0.08 | 0.68 ± 0.09 | 0.95 | 0.57 ± 0.08 | 0.80 ± 0.09 | 0.07 |
SF-36 | |||||||||
Physical functioning | 71.3 ± 6.5 | 73.8 ± 3.2 | 0.74 | 73.5 ± 4.3 | 68.1 ± 4.3 | 0.38 | 81.7 ± 3.8 | 59.9 ± 4.3 | <0.001 |
Role – physical | 70.6 ± 13.4 | 50.4 ± 6.6 | 0.18 | 70.3 ± 8.2 | 38.0 ± 8.3 | 0.009 | 55.6 ± 7.2 | 52.7 ± 8.2 | 0.80 |
Bodily pain | 58.8 ± 9.4 | 65.2 ± 4.7 | 0.54 | 72.2 ± 5.6 | 55.3 ± 5.6 | 0.04 | 66.9 ± 5.0 | 61.0 ± 5.8 | 0.44 |
General health | 49.6 ± 8.8 | 56.0 ± 4.5 | 0.52 | 61.0 ± 5.2 | 51.6 ± 5.2 | 0.21 | 60.8 ± 4.9 | 51.8 ± 5.5 | 0.23 |
Vitality | 61.6 ± 7.3 | 51.0 ± 3.7 | 0.20 | 58.4 ± 4.2 | 48.7 ± 4.2 | 0.11 | 57.4 ± 3.9 | 49.8 ± 4.6 | 0.22 |
Social functioning | 70.3 ± 8.1 | 81.3 ± 4.1 | 0.23 | 81.7 ± 4.9 | 77.9 ± 5.0 | 0.6 | 85.4 ± 4.5 | 74.3 ± 5.2 | 0.12 |
Role – emotional | 71.1 ± 11.4 | 76.8 ± 5.7 | 0.66 | 85.4 ± 6.7 | 67.3 ± 7.1 | 0.08 | 81.4 ± 6.4 | 72.0 ± 7.3 | 0.35 |
Mental health | 73.3 ± 6.2 | 76.7 ± 3.1 | 0.62 | 78.1 ± 3.6 | 76.4 ± 3.7 | 0.75 | 79.8 ± 3.4 | 74.7 ± 3.9 | 0.34 |
*adjusted for age, sex and comorbidity
** adjusted for sex and comorbidity
*** adjusted for age and sex