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. 2006 Nov 16;7:17. doi: 10.1186/1471-2369-7-17

Table 5.

Health-related quality of life scores according to immunosuppressive regimen, age below/above the median and comorbidity below/above the median

Ciclosporin* Age (years)** Charlson comorbidity index***



Tacrolimus and prednisolon Ciclosporin and prednisolon p ≤58.88 >58.88 p ≤2 >2 p


N 9 39 27 26 30 23
ESRD-SCL
Limited physical capacity 0.62 ± 0.18 0.82 ± 0.09 0.33 0.73 ± 0.11 0.81 ± 0.11 0.62 0.63 ± 0.10 0.91 ± 0.11 0.06
Limited cognitive capacity 0.45 ± 0.15 0.59 ± 0.08 0.43 0.57 ± 0.10 0.58 ± 0.10 0.93 0.46 ± 0.09 0.69 ± 0.10 0.10
Cardiac and renal dysfunction 0.72 ± 0.19 0.82 ± 0.08 0.21 0.73 ± 0.11 0.79 ± 0.11 0.71 0.62 ± 0.10 0.91 ± 0.12 0.07
Side effects of corticosteroids 0.67 ± 0.18 0.68 ± 0.09 0.20 0.71 ± 0.11 0.58 ± 0.11 0.16 0.53 ± 0.10 0.76 ± 0.12 0.16
Increased growth of gum and hair 0.19 ± 0.27 0.92 ± 0.09 0.02 0.74 ± 0.16 0.73 ± 0.16 0.98 0.61 ± 0.15 0.87 ± 0.17 0.26
Transplantation-associated psychological distress 0.67 ± 0.16 0.58 ± 0.08 0.60 0.66 ± 0.09 0.54 ± 0.09 0.38 0.56 ± 0.09 0.64 ± 0.10 0.56
Total 0.57 ± 0.14 0.73 ± 0.07 0.32 0.69 ± 0.08 0.68 ± 0.09 0.95 0.57 ± 0.08 0.80 ± 0.09 0.07
SF-36
Physical functioning 71.3 ± 6.5 73.8 ± 3.2 0.74 73.5 ± 4.3 68.1 ± 4.3 0.38 81.7 ± 3.8 59.9 ± 4.3 <0.001
Role – physical 70.6 ± 13.4 50.4 ± 6.6 0.18 70.3 ± 8.2 38.0 ± 8.3 0.009 55.6 ± 7.2 52.7 ± 8.2 0.80
Bodily pain 58.8 ± 9.4 65.2 ± 4.7 0.54 72.2 ± 5.6 55.3 ± 5.6 0.04 66.9 ± 5.0 61.0 ± 5.8 0.44
General health 49.6 ± 8.8 56.0 ± 4.5 0.52 61.0 ± 5.2 51.6 ± 5.2 0.21 60.8 ± 4.9 51.8 ± 5.5 0.23
Vitality 61.6 ± 7.3 51.0 ± 3.7 0.20 58.4 ± 4.2 48.7 ± 4.2 0.11 57.4 ± 3.9 49.8 ± 4.6 0.22
Social functioning 70.3 ± 8.1 81.3 ± 4.1 0.23 81.7 ± 4.9 77.9 ± 5.0 0.6 85.4 ± 4.5 74.3 ± 5.2 0.12
Role – emotional 71.1 ± 11.4 76.8 ± 5.7 0.66 85.4 ± 6.7 67.3 ± 7.1 0.08 81.4 ± 6.4 72.0 ± 7.3 0.35
Mental health 73.3 ± 6.2 76.7 ± 3.1 0.62 78.1 ± 3.6 76.4 ± 3.7 0.75 79.8 ± 3.4 74.7 ± 3.9 0.34

*adjusted for age, sex and comorbidity

** adjusted for sex and comorbidity

*** adjusted for age and sex