Figure 4.

Ex vivo IR-MEIs from the same slice orientations as those images in Figs. 3-c, d and e. a) Mn-enhanced CST rostral to the injury. b) Mn-enhancement at the epicenter of the injury. c) Mn-labelling of the CST caudal to the injury. The partial signal enhancement, depicted by the arrowhead in b, is likely to represent a portion of the CST that is populated with intact fibers. By continuously projecting through the injury site, these intact fibers transport Mn from rostral to caudal sections, as indicated by the presence of focal signal enhancement in c.