Table 7.

Clinical and histologic differences between ANCA (+) and ANCA (-) patients

	ANCA (+) N = 26	ANCA (-) N = 8	p
I. Clinical
Age (years)	60 ± 13	42 ± 20	0,005
pCreatinine at biopsy (mg/dl)	6.11 ± 4.7	5.7 ± 1.8	NS
pUrea at biopsy (mg/dl)	128.3 ± 69.3	109.4 ± 25.5	NS
CRP (mg/l)	64.7 ± 75	99 ± 86	NS
ESR (mm/1 h)	116 ± 28	108 ± 44	NS
24 h urinary albumin excretion (g)	2.21 ± 1.12	1.17 ± 0.77	0,005
II. Histologic
Crescents (%)	63 ± 33	52 ± 32	NS
Cellular crescents	59 ± 44	51 ± 47	NS
Fibrocellular crescents	11 ± 26	51 ± 47	NS(0.06)
Fibrous crescents	12 ± 24	11 ± 21	NS
Obsolete glomeruli	25 ± 23	35 ± 19	NS
Focal necrosis	1.34 ± 0.48	1.62 ± 0.52	NS
TIN infiltration	1.36 ± 1.13	1.87 ± 0.99	NS
Tubular atrophy	1.13 ± 0.97	1.5 ± 0.93	NS
TIN fibrosis	1.4 ± 1.1	1.59 ± 0.5	NS
Arterial sclerosis	1.79 ± 1.06	2.25 ± 0.96	0.05

Abbrev: CRP, C-reactive protein, ESR, erythrocyte sedimentation rate, TIN, tubulointerstitial