Table 9.

Clinical and histologic differences between MPO-ANCA (+) and PR3-ANCA (+) patients

	MPO-ANCA (+) N = 17	PR3-ANCA (+) N = 9	p
I. Clinical
Age (years)	63 ± 10	55 ± 17	NS
pCreatinine at biopsy (mg/dl)	5.9 ± 4.5	6.5 ± 5.3	NS
pUrea at biopsy (mg/dl)	123 ± 56	138 ± 92	NS
CRP (mg/l)	54 ± 63	84 ± 95	NS
ESR (mm/1 h)	116 ± 34	116 ± 16	NS
24 h urinary albumin excretion (g)	1.24 ± 0.81	1.04 ± 0.73	NS
II. Histologic
Crescents (%)	61 ± 35	67 ± 28	NS
Cellular crescents	56 ± 44	66 ± 46	NS
Fibrocellular crescents	13 ± 30	8 ± 17	NS
Fibrous crescents	10 ± 21	15 ± 31	NS
Obsolete glomeruli	28 ± 22	20 ± 24	NS
Focal necrosis	1.41 ± 0.5	1.22 ± 0.44	NS
TIN infiltration	1.53 ± 1.12	1.0 ± 1.15	NS
Tubular atrophy	1.4 ± 0.98	0.62 ± 0.74	NS
TIN fibrosis	1.5 ± 1.09	1.07 ± 1.09	NS
Arterial sclerosis	1.94 ± 1.0	1.5 ± 1.19	NS

Abbrev: CRP, C-reactive protein, ESR, erythrocyte sedimentation rate, TIN, tubulointerstitial