Figure 4.

Map of the new deficiency allele (Adar^SD23) for the Adar gene and sequencing records of wild-type Canton-S, the mutant, and a revertant line from the same genetic background. Exon-intron structure of the Adar gene with base ruler (in kb, modified from FlyBase) and position of the 1,197 bp deficiency in the Adar^SD23 allele (top panel). The arrows in the lower three panels point to the base of the second codon of the kinase target motif that is edited in all wild-type strains investigated and in the revertant, but not in the mutant. In the wild type Canton-S an additional partial editing is observed in the first arginine codon indicated by overlapping peaks in the record (asterisks).