TABLE 2.
MICs of various aminoglycosides for K. pneumoniae BM4536 and E. coli with and without the armA gene
| Strain | MIC (μg/ml)a
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| AMI | GEN | ISE | NET | TOB | APR | PAR | STR | SPE | |
| K. pneumoniae BM4536 | 512 | 256 | 512 | 256 | 512 | 1 | 2 | 32 | >256 |
| E. coli | |||||||||
| BM694 | 2 | 0.5 | 0.5 | 0.5 | 0.5 | 2 | 4 | 4 | 8 |
| BM694(pIP1204) | 1,024 | 256 | 1,024 | 256 | 256 | 2 | 4 | 8 | 256 |
| INVαF′ | 1 | 0.25 | 0.5 | 0.25 | 0.25 | 0.5 | 0.5 | 1 | 4 |
| INVαF′(pAT780) | 512 | 256 | 512 | 256 | 128 | 0.5 | 0.5 | 1 | 8 |
| INVαF′(pAT781) | 512 | 256 | 256 | 256 | 128 | 0.5 | 0.5 | 1 | 8 |
| INVαF′(pAT782) | 256 | 128 | 256 | 128 | 128 | 0.5 | 0.5 | 1 | 8 |
a
Abbreviations: AMI, amikacin; GEN, gentamicin; ISE, isepamicin; NET, netilmicin; TOB, tobramycin; APR, apramycin; PAR, paromomycin; STR, streptomycin; SPE, spectinomycin.