TABLE 3.
Peptide code | Concn (fold MIC) | Pathogen | Maximal killing (% bacteria killed) | Time when maximal killing was reached |
---|---|---|---|---|
NRC-1 | 1 | 99-1 | 100 | 40 |
10 | 99-1 | 100 | 20 | |
1 | MS7953s | 100 | 20 | |
10 | MS7953s | 100 | 10 | |
1 | C. albicans | NK | NA | |
10 | C. albicans | 90 | 240 | |
NRC-3 | 1 | 99-1 | 90 | 20 |
10 | 99-1 | 100 | 5 | |
1 | MS7953s | 97 | 60 | |
10 | MS7953s | 100 | 20 | |
NRC-12 | 1 | C. albicans | NK | NA |
10 | C. albicans | 90 | 240 | |
NRC-13 | 1 | K799 | 95 | 10 |
10 | K799 | 100 | 5 | |
NRC-13 with NaCl | 1 | K799 | 5 | 60 |
10 | K799 | 100 | 20 | |
NRC-13 | 1 | MRSA | 99 | 10 |
10 | MRSA | 100 | 5 | |
1 | C. albicans | 25 | 240 | |
10 | C. albicans | 75 | 240 | |
NRC-15 | 1 | K799 | 60 | 60 |
10 | K799 | 98 | 10 | |
1 | MRSA | 100 | 20 | |
10 | MRSA | 100 | 5 | |
NRC-16 | 1 | C. albicans | 35 | 240 |
10 | C. albicans | 92 | 240 | |
NRC-17 | 1 | C. albicans | 10 | 240 |
10 | C. albicans | 95 | 240 | |
NRC-19 | 1 | MRSA | 33 | 60 |
10 | MRSA | 90 | 10 | |
1 | K799 | 70 | 60 | |
10 | K799 | 80 | 40 |
The bacterial strains used are A. salmonicida (99-1), S. typhimurium (MS7953s), P. aeruginosa (K799), and MRSA. NK, no killing; NA, not available.