TABLE 2.

MICs and MBCs of newer antibiotics for 11 serovars of Leptospira

Species and serovar	MIC (MBC)
	Ampicillin-sulbactama	Cefotaxime	Ceftriaxone	Azithromycin	Telithromycin	Ciprofloxacin	Moxifloxacin
L. biflexa, Patoc	0.05 (0.10)	0.05 (0.10)	0.10 (0.39)	≤0.01 (0.39)	≤0.01 (0.20)	≤0.01 (1.56)	≤0.01 (3.13)
L. borgpetersenii, Ballum	0.02 (0.05)	≤0.01 (0.02)	0.05 (0.10)	0.02 (0.05)	≤0.01 (≤0.01)	0.10 (12.5)	0.10 (12.5)
L. borgpetersenii, Sejroe	0.05 (0.10)	≤0.01 (≤0.01)	0.02 (0.10)	≤0.01 (≤0.01)	≤0.01 (≤0.01)	0.39 (25)	0.20 (12.5)
L. interrogans, Copenhageni	0.02 (0.10)	≤0.01 (0.05)	0.02 (0.20)	0.05 (0.20)	≤0.01 (≤0.01)	0.20 (0.78)	0.10 (0.20)
L. interrogans, Grippotyphosa	0.02 (0.05)	≤0.01 (0.05)	0.02 (0.10)	≤0.01 (≤0.01)	≤0.01 (≤0.01)	0.05 (0.10)	0.05 (0.10)
L. interrogans, Icterohaemorrhagiae	0.02 (0.05)	≤0.01 (0.10)	≤0.01 (0.78)	≤0.01 (0.39)	≤0.01 (≤0.01)	0.10 (12.5)	0.10 (3.13)
L. interrogans, Pomona	0.02 (0.10)	0.02 (0.05)	0.10 (0.39)	≤0.01 (1.56)	≤0.01 (0.10)	0.10 (12.5)	0.05 (12.5)
L. kirschner, Butembo	0.05 (0.20)	0.05 (0.10)	0.20 (0.20)	≤0.01 (≤0.01)	≤0.01 (≤0.01)	0.20 (0.20)	0.10 (0.10)
L. noguchii, Fortbragg	≤0.01 (0.05)	≤0.01 (≤0.01)	≤0.01 (0.10)	≤0.01 (0.78)	≤0.01 (0.05)	0.10 (12.5)	0.05 (12.5)
L. santarosai, Alexi	0.05 (0.10)	0.10 (0.20)	0.20 (0.39)	≤0.01 (0.39)	≤0.01 (0.10)	0.10 (25)	0.10 (12.5)
L. weilii, Celledoni	0.02 (0.05)	0.05 (0.05)	0.10 (0.10)	≤0.01 (0.02)	≤0.01 (≤0.01)	0.10 (0.20)	0.10 (0.10)
MIC90 (MBC90)	0.05 (0.10)	0.05 (0.10)	0.20 (0.39)	0.02 (0.78)	≤0.01 (0.10)	0.20 (25)	0.10 (12.5)

^aAmpicillin-sulbactam was used in a 2:1 mixture; results are reported by ampicillin content.