Table 1.
Characteristics of main Activated Clotting Time (ACT) instruments for high-dose heparin therapy.
| INSTRUMENT (Manufacturer) | ASSAY | ACTIVATORS | SAMPLE SIZE | SAMPLE TYPE |
| HEMOCHRON Series (ITC, USA) | ACT | Celite or Kaolin | 2 mL | FWB |
| HEMOCHRON JR II and SIGNATURE (ITC, USA) | ACT+ | Kaolin, silica and phospholipids | 1 drop | FWB |
| ACT II, HEPCON HMS (Medtronic, USA) | ACT, HEMOSTATUS | Kaolin or celite | 0.4 mL (×2) | FWB |
| RAPIDPOINT COAG (Bayer, USA) | HMT | Celite | 1 drop | FWB CWB |
| I-STAT (ABBOTT, USA) | Celite-ACT | Celite | 40 microL | FWB |
| COAGUCHEK PRO (Roche Diagnostics, USA) | ACT | Celite | 1 drop | FWB |
| ACTALYKE (ARRAY | 1) ACT | 1) Celite or kaolin | 1) 1 mL | FWB |
| MEDICAL, USA) | 2) MAX-ACT | 2) Celite, kaolin and glass cocktail | 2) 0.5 mL | |
| SONOCLOT (Sienco, USA) | SONACT | Celite | 0.4 mL | FWB CWB |
ACT, activated clotting time; FWB, fresh whole blood; CWB, citrated whole blood.