Table 3.
Effects of tetrapyrroles on cell viability and growth.
| Compound | CC50 (µg/mL) | |
| Cytostatic activitya | Cell proliferationb | |
| ZnPPIX | 370 | 25 |
| CuPcS(3444) | > 1000 | > 500 |
| TNapPS | 400 | |
| TAnthPS | 350 | 120 |
| TPP[2,6-(OH)2] | 90 | 20 |
| CuHPIX | 36 | |
| Co(III)TPP(2,6-F2)S | 300 | < 5 |
aCV-1 cells were seeded at 3.5 × 103 cells/well and allowed to attach overnight, then the compounds (in growth medium) added. Following 24 h incubation, the cells were counted. bThese results were obtained by measuring 3H-thymidine uptake using HeLa S3 cells.