Table 5.

Inhibition of virus yield after removal of tetrapyrroles before cell lysis.^a

Compound	Concentration
	25 µg/mL		50 µg/mL
	titer (pfu/mL)	% inhibition	titer (pfu/mL)	% inhibition
TNapPS	3.5 × 105	73 ± 16	1.0 × 105	92 ± 1
TAnthPS	1.2 × 106	39 ± 13	7.5 × 105	67 ± 15
CuHPIX	1.3 × 106	33 ± 9	6.3 × 105	71 ± 4
CuPcS(3444)	9.3 × 105	49 ± 21	8.3 × 105	59 ± 2
ZnPPIX	7.2 × 105	65 ± 0.3	6.4 × 105	70 ± 4

^aCV-1 cells were infected at 2.5 pfu/cell and then treated with compounds at 50 or 25 µg/mL; at 16 h post-infection, the medium was removed and cells were washed and harvested for virus titration by plaque assay. Virus titer in the control was 2.1 × 10⁶ pfu/mL. Data are expressed as means ± std of triplicate experiments, each replicated twice. % inhibition was calculated as described in Table 4.