Table 6.
Serum Immunoglobulin Concentrations in Index Patients with Significantly Associated HLA-A and -B Haplotypes.1
| Number of Significantly Associated Haplotypes | 0 | 1 | 2 |
| Serum IgG, mg/dL (n) | 734 ± 273 (45) | 735 ± 287 (112) | 749 ± 257 (33) |
| Serum IgA, mg/dL (n) | 167 ± 92 (48) | 157 ± 117 (109) | 169 ± 71 (33) |
| Serum IgM, mg/dL (n) | 108 ± 70 (46) | 116 ± 96 (110) | 115 ± 108 (34) |
1 These data are expressed as mean ± 1 SD. Significantly associated haplotypes were defined as those that occurred with significantly greater frequency in CVID and IgGSD index cases than in control subjects. These six haplotypes were: A*01-B*08, A*02-B*44, A*03-B*07, A*03-B*14, A*31-B*40, and A*32-B*14 (see Table 4). There were no significant differences in the mean values of IgG, IgA, or IgM in the index patients grouped by inheritance of significantly associated haplotypes.