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. Author manuscript; available in PMC: 2007 Jan 1.
Published in final edited form as: Neurobiol Dis. 2006 Sep 28;25(1):73–79. doi: 10.1016/j.nbd.2006.08.009

Figure 1.

Figure 1

Determination of the critical period in males. The flurothyl seizure threshold for the first clonic seizure was determined at PN15 in male rats castrated at PN3. The rats were thus exposed to natural testosterone for three days. Muscimol infusions in the SNR had proconvulsant effects compared to saline-infused controls suggesting that exposure to natural testosterone during the early postnatal period is responsible for the male proconvulsant phenotype of seizure-controlling SNR effects. The asterisk indicates a significant difference (P < 0.05) from saline-infused control.