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Significant potential drug interactions
| Drug pair | Possible effects |
|---|---|
| Atenolol + nifedipine | Severe hypotension and heart failure occasionally |
| Phenytoin + folic acid | Decrease plasma level of phenytoin |
| Simvastatin + erythromycin | Increase risk of myopathy |
| Simvastatin + warfarin | Enhanced anticoagulant effect |
| SSRI + valproate | Convulsion threshold lowered |
| Theophylline + calcium channel blocker | Possibly enhanced theophylline effect |
Abbreviation: SSRI, selective serotonin reuptake inhibitor.
