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. 2006 Nov 28;4(12):e423. doi: 10.1371/journal.pbio.0040423

Figure 4. Fluorescence Visualization of an ER Marker after UPR Induction.

Figure 4

(A) Cells treated with the UPR-inducing drug DTT (+DTT) or with no drug were visualized using a fusion protein between the translocon component Sec61 and the red-fluorescent protein “cherry.” Top panels show untreated cells, and bottom panels show representative UPR-induced cells.

(B) Representative images showing UPR-induced cells that contain ERAs (indicated by arrows).