Table 5. Stable, potent inhibition of PC7 by Arg-40-Arg-42-Arg-45-eglin.

	Kex2	Furin	PC7
Met-42-Arg-45-eglin	3.4 × 10-10*	3.6 × 10-6*	3.2 × 10-6
Arg-42-Arg-45-eglin	9.1 × 10-10*	2.5 × 10-9*	1.3 × 10-9
Arg-40-Met-42-Arg-45-eglin	5.3 × 10-10	2.7 × 10-6	2.4 × 10-7
Arg-40-Arg-42-Arg-45-eglin	2.9 × 10-11*	2.8 × 10-9*†	6.7 × 10-10

All values were determined by using purified inhibitors as described in Materials and Methods. Experimental errors were ±20%

^*Published values from ref. 11 are provided for comparison

^†Temporary inhibition