Table 3. Putative transcript factor binding sites in promoter region of DYRK1A.
| Position* | Variation human/Pan | Human binding site | Chimpanzee binding site |
|---|---|---|---|
| 297872 | G/A | V$GFI1_01 | V$GFI1_01 |
| aagaagaaAATCgtatctgtagct | aagaagaaAATCatatctgtagct | ||
| 297947 | T/C | V$DELTAEF1_01 tctgACCTtgt | Lost the binding site |
| 297976 | G/A | No binding site | V$AP1_Q4: agTGACtagcc |
| 298278 | G/T | No binding site | No binding site |
| 298428 | G/A | V$HNF3B_01: AtttaTGTTttcttt | V$HNF3B_01: atttaTATTttcttt |
| Lost the binding site | V$TATA_01: ataTAAAttcaatct |
*
The number from GenBank accession no. AP001728. The ATG was located in 300202