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. 2003 Jun 26;100(14):8395–8400. doi: 10.1073/pnas.1332805100

Fig. 5.

Fig. 5.

NK cells in αGalCer-primed mice and IL-12Rβ2-/- mice produce less IFN-γ.(A) Intracellular IFN-γ content of DX5+TCRβ- cells from the liver 6 h after αGalCer injection. Percentages of IFN-γ+ (boldface line) or isotype+ cells are indicated. One representative mouse is shown for each strain. For WT, n = 5; primed mice, n = 5; and IL-12Rβ2-/- mice, n = 4. (B) Comparison of IFN-γ levels in sera 6 h after αGalCer injection in WT, asialo-GM1 treated, and IL-12Rβ2-/- mice. One representative experiment of two is shown. Statistical analysis was performed by using t tests to compare IFN-γ levels in WT versus GM1-treated and IL-12Rβ2-/- mice. *, P = 0.003; **, P = 0.005.