Fig. 2.

Characteristic tissue lesions in 129/Sv mice with graft-versus-host disease after the injection of syngeneic Socs1^-/- marrow cells. (a) Liver, with cuffing of portal tract vessels by lymphocytes, macrophages, and plasma cells is shown. (b) Liver, with a focal granuloma of neutrophils, lymphocytes, and plasma cells together with multinucleate giant cells is shown. (c) Lung, with thickening of alveolar walls by lymphocytes and macrophages and a small area of pneumonia is shown. (d) Kidney, with focal infiltrate of plasma cells adjacent to a glomerulus, is shown.