Transcriptome of jasmonate-elicited BY-2 cells. (A) Average
linkage hierarchical clustering of MJM gene tags. The time points for the
cluster analysis are indicated (in hours) at the top. Red and green boxes
reflect transcriptional activation and repression, respectively, relative to
the average expression level in control (DMSO) cells. Gray boxes correspond to
missing time points. Pink and black parts of the dendrogram indicate the
clusters of activated and repressed genes, respectively. (B)
Biosynthetic pathway of nicotine alkaloids. Enzymes involved in the metabolic
conversions are in red, those for which the corresponding tobacco gene or
orthologs from other plants have been cloned are boxed, and those for which a
corresponding MJM tag has been identified in the transcript profiling analysis
are in yellow. (C) Subcluster of the MJM transcriptome. Shown is a
close-up of a subcluster comprising gene tags coregulated with genes known to
be involved in nicotine biosynthesis. (D) Average linkage
hierarchical clustering of tags common between the MJM transcriptome and the
genes differentially expressed in tobacco roots
(50). The corresponding
protein (PR) code, as used previously
(50), has been included.
(E) Expression analysis of pmt. Expression of pmt
was verified by RT-PCR analysis on the RNA prepared for cDNA-AFLP transcript
profiling and using oligonucleotides spanning nucleotides 8–897 of the
N. tabacum cv. Burley pmt ORF
(38). Time points are
indicated (in hours) at the top of the ethidium bromide-stained gel.
(F) Average linkage hierarchical clustering of signal transducing
genes common between the MJM transcriptome and the wound-induced
Arabidopsis transcriptome
(33). The corresponding Munich
Information Center for Protein Sequences code has been included. ADC, arginine
decarboxylase; AG, arginase; AP, aspartate oxidase; LDC, lysine decarboxylase;
MEJA, methyl jasmonate; MPO, methylputrescine oxidase; ODC, ornithine
decarboxylase; PMT, putrescine methyltransferase; QPRT, quinolinate
phosphoribosyltransferase.