FIG. 5.
ΔNp73 cooperates with cMyc and E1A in cell proliferation and colony formation. (A) Morphology of 129 MEFs infected with retroviruses expressing GFP only, ΔNp73 only, cMyc only, or cMyc together with wild-type or mutant ΔNp73. mtΔNp73 stands for ΔNp73 L322P. (B) Colony formation assay of MEFs transduced with the indicated plasmids. The bar graph shows the quantitation of three independent experiments plus the standard deviation. (C) Short-term growth curve of MEFs infected with retroviruses coexpressing either E1A and GFP or E1A and ΔNp73.
