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Subcellular localization of DMPK isoforms and mutants in COS-1 cells. COS-1 cells were transfected with expression vectors encoding DMPK isoforms and mutants and grown for 24 h. Cells were fixed with 2% formaldehyde and stained with a DMPK-specific antibody. The isoform or mutant shown is indicated in the lower left of each panel. Bar,10 μm. The insets in A, C, and E show a higher magnification of parts indicated with an arrow. The bar in the insets is 2 μm.
