FIG. 3.
CO-FISH primary MEFs. (Left panel) Frequency of chromosome-type or chromatid-type fusions involving telomeres produced by leading-strand synthesis in metaphases of the indicated genotypes. (+)TTAGGG, fusions showing TTAGGG signal at the fusion point; (−)TTAGGG, fusions lacking TTAGGG signal at the fusion point. (Right panels) Representative CO-FISH images of chromosome-type telomere fusions containing TTAGGG repeats at the fusion point (yellow arrows) in the indicated individual MEF. Blue, DAPI; red, TTAGGG signal.
