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. 2003 Aug;23(16):5614–5624. doi: 10.1128/MCB.23.16.5614-5624.2003

FIG. 1.

FIG. 1.

Expression of ADAM15 mRNA in mouse embryos. All sections were hybridized with an antisense ADAM15 probe (as described in Materials and Methods). Digital images were obtained by bright-field (A, D, and E) and dark-field (B, C, and F) microscopy. (A and B) Section of E9.5 embryo, showing a prominent expression in mesenchymal tissue in the developing head (red arrows), developing heart (HT), arteries (blue arrows). Scale bar, 100 μm. (C) Section of the heart of an E11.5 embryo. Strong expression was observed in the surface lining the ventricle (VT), atrium (AT), and bulbus arteriosus (BA). Scale bar, 200 μm. (D) Bright-field view (magnification, ×400) of the ventricle of an E13.5 embryo shows high-level expression in the endocardium (arrowheads). Scale bar, 50 μm. (E and F) In the cartilage primordium of occipital bone of an E16.5 embryo, positive signals can be seen in hypertrophic cells (arrowheads). Scale bar, 200 μm.