FIG. 6.

Coding joints mediated by mutant ABCDE have minimal nucleotide loss from joined ends. The sequences of coding ends as they occur in the pJH290 substrate are shown above the sequences of the recombinant junctions. The number of observations of each sequence is given in parentheses to the right of the sequence. All duplicate sequences were derived from separate transfections. Nucleotides in columns headed by “p” are palindromic nucleotides added to each junction. Nucleotides that cannot be unequivocally assigned to a particular coding end are underlined and listed in the 5′-most location. Portions of the wild-type (WT) and RAG-only coding joints are from references 21 and 49.