Fig. 1.

Behavioral recovery is improved in double mutant mice. (A) Time to cross the grid was evaluated during the training period before the SCI and the second and fourth weeks after hemisection. Wild-type and double mutant mice took a significantly longer time to cross the grid after the lesion (P < 0.001, Mann–Whitney U test). (B) Numbers of footfalls of the impaired hindlimb made by wild-type and double mutant mice were evaluated during the second and fourth weeks after the hemisection (n = 7). Error bars indicate standard errors.