Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The eight general karyotypic classes detected in 23 cell populations resistant to 100 nM methotrexate. Each panel corresponds to one of the eight karyotypes that were detected with a 5 paint/DHFR cosmid FISH combination. The number of DMs varied among cells and among populations from several to >100.
