Figure 7.

The anti-repulsive guidance molecule (anti-RGM) A antibody, but not the IgG control antibody, promotes the regeneration of corticospinal tract axons after spinal cord injury. Camera lucida drawings of biotin-dextran-amine labelled corticospinal axons of a (a) control IgG-treated rat and an (b) anti-RGM A antibody-treated rat in consecutive parasagittal sections. Grey-coloured tissue corresponds to scar tissue at or adjacent to the transection injury lesion. Reproduced from the Journal of Cell Biology 2006; 173, 47–58 by copyright permission of the Rockefeller University Press.