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. 2006 Jul 5;2006:96341. doi: 10.1155/PPAR/2006/96341

Figure 3.

Figure 3

Figure 3

Antiedema effect of the PPARδ agonist L-738483 on carrageenan-induced paw edema in wild-type and hepatocyte-specific RXRα-deficient mice. Wild-type (a) and hepatocyte-specific RXRα-deficient mice (b) were treated intraperitoneally with (100 mg/kg) of L-738484, 30 minutes before induction of inflammation. As indicated by the arrow, carrageenan (1%, intraplantar) was injected at t = 0. Carrageenan-induced edema is reflected by an increase in paw thickness. Values represent mean ±SEM. n = 3–5 mice per group. *P < .05 versus corresponding wild-type point.