Figure 4. Effect of 48 h fasting from solid food on the depression of bradykinin-induced plasma extravasation by intradermal capsaicin in the hind paw.

>The depression of bradykinin plasma extravasation by the intraplantar injection of capsaicin (3, 10 and 30 μg i.d.) in rats that were fasted for 48 h (t) was enhanced, compared to fed rats (○ from Fig. 1). The magnitude of enhancement induced by fasting was similar to the magnitude of that induced by subdiaphragmatic vagotomy (•; from Fig. 1).