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I–V relationship (–127 to –57 mV in 10 mV increments) in the presence of (TTX, 0.5 μm) under (A) control conditions (Vh–87 mV) and (B) after addition of tolbutamide (100 μm). C, the tolbutamide-sensitive component of current exhibits no fast kinetic activation or inactivation. D, the I–V curve of the steady state (end of pulse) tolbutamide-sensitive current shown in B.
