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. 2003 Oct 24;554(Pt 3):659–672. doi: 10.1113/jphysiol.2003.055806

Figure 5. Irreversible block of Is by 10 μm clofilium, a non-selective blocker of K+ currents.

Figure 5

A, voltage protocol. Current traces are shown at +20 mV (Is) and at +70 mV (Ir+Is) under control conditions (B), in the presence of 10 μm clofilium (C) and after washout (D). The current–voltage relation in the absence and presence of clofilium shows selective inhibition of Is without major block of Ir (E; hMSC from the 4th passage).