Figure 2. Hypotonicity-induced [³H]taurine efflux from rat pituicytes.

A, taurine efflux induced by a 270 mosmol l⁻¹ hypotonic shock applied (as indicated by the bar) to non-stellate pituicytes (continuous line; n = 12) or stellate pituicytes (dashed line; n = 6). The dotted line shows glutamate efflux, which is not affected by the 270 mosmol l⁻¹ medium (n = 4). The latter consisted of Locke's medium without mannitol (see Methods). B, efflux induced by a 200 mosmol l⁻¹ shock applied to non-stellate pituicytes (n = 4). The 200 mosmol l⁻¹ medium was prepared by diluting the 270 mosmol l⁻¹ solution with water. In this and subsequent figures, efflux is a unitless ratio normalized to baseline (see Methods).