Figure 6. Modulation of VP-induced [³H]taurine efflux from rat pituicytes.

A, efflux induced by 10 nm VP in the absence (continuous line; n = 7) or in the presence (dashed line; n = 6) of 1 mm DIDS. B, efflux induced by 10 nm VP in 300 mosmol l⁻¹ medium (continuous line; same data as control in Fig. 2B) or in 330 mosmol l⁻¹ medium preapplied for 10 min (dashed line; n = 3). Hypertonic solution was prepared by adding 30 mm mannitol to Locke's medium.