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. 2003 Dec 12;555(Pt 1):85–96. doi: 10.1113/jphysiol.2003.056986

Figure 3. Stronger inhibition by WIN of C-fibre EPSPs than Aδ-fibre EPSPs.

Figure 3

A, averaged time course of the inhibitory effect of WIN (5 μm) on monosynaptic Aδ-fibre EPSPs (n= 5). B, averaged time course showing the effect of WIN on monosynaptic C-fibre EPSPs (n= 7). Insets show superimposed EPSPs taken at the indicated times (1–3). C, comparison between the magnitude of the WIN-induced EPSP inhibition (ordinate, 20 min after WIN application) and the synaptic latency of EPSPs (abscissa). A regression line was drawn using the least squares method (r= 0.89). D, dose–response curves for depression of Aδ- (◯) and C-fibre EPSPs (•) by WIN. The numbers in parentheses indicate the number of slices tested.