Figure 4. Contribution of β-adrenoceptors to skin cooling-induced thermogenesis.
Effects of propranolol (10 mg kg−1, i.v., arrow in B) on skin cooling-induced changes in Ts (A) and V̇O2 (B). The horizontal bars ‘c’ and ‘d’ in B show the periods of the EMG records shown in C and D, respectively. The arrows in C and D show the onset of cooling stimulation. Administration of propranolol had no effect on the cooling-induced EMG activity. E, cooling-induced increase in V̇O2 before and after administration of propranolol in five rats, showing significant attenuation of thermogenesis. Each set of symbols and connecting lines indicates an individual rat.